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Rhodes, Christopher
One or more keywords matched the following items that are connected to
Rhodes, Christopher
Item Type
Name
Concept
RNA, Messenger
Academic Article
Glucose-regulated translational control of proinsulin biosynthesis with that of the proinsulin endopeptidases PC2 and PC3 in the insulin-producing MIN6 cell line.
Academic Article
Specific co-ordinated regulation of PC3 and PC2 gene expression with that of preproinsulin in insulin-producing beta TC3 cells.
Academic Article
The ratio of mouse insulin I:insulin II does not reflect that of the corresponding preproinsulin mRNAs.
Academic Article
Chronic exposure to free fatty acid reduces pancreatic beta cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation.
Academic Article
A specific increased expression of insulin receptor substrate 2 in pancreatic beta-cell lines is involved in mediating serum-stimulated beta-cell growth.
Academic Article
Cooperativity between the preproinsulin mRNA untranslated regions is necessary for glucose-stimulated translation.
Academic Article
Cysteine string protein (CSP) is an insulin secretory granule-associated protein regulating beta-cell exocytosis.
Academic Article
Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation.
Academic Article
Insulin secretory deficiency and glucose intolerance in Rab3A null mice.
Academic Article
Arcuate nucleus-specific leptin receptor gene therapy attenuates the obesity phenotype of Koletsky (fa(k)/fa(k)) rats.
Academic Article
Glucose-induced translational control of proinsulin biosynthesis is proportional to preproinsulin mRNA levels in islet beta-cells but not regulated via a positive feedback of secreted insulin.
Academic Article
Specific regulation of IRS-2 expression by glucose in rat primary pancreatic islet beta-cells.
Academic Article
A cis-element in the 5' untranslated region of the preproinsulin mRNA (ppIGE) is required for glucose regulation of proinsulin translation.
Academic Article
Involvement of Per-Arnt-Sim Kinase and extracellular-regulated kinases-1/2 in palmitate inhibition of insulin gene expression in pancreatic beta-cells.
Academic Article
Exendin 4 controls insulin production in rat islet beta cells predominantly by potentiation of glucose-stimulated proinsulin biosynthesis at the translational level.
Academic Article
The balance between proinsulin biosynthesis and insulin secretion: where can imbalance lead?
Academic Article
FoxO feedback control of basal IRS-2 expression in pancreatic ß-cells is distinct from that in hepatocytes.
Academic Article
Mechanism of action of glucagon-like peptide-2 to increase IGF-I mRNA in intestinal subepithelial fibroblasts.
Academic Article
Specific glucose-induced control of insulin receptor substrate-2 expression is mediated via Ca2+-dependent calcineurin/NFAT signaling in primary pancreatic islet ß-cells.
Academic Article
Palmitate inhibition of insulin gene expression is mediated at the transcriptional level via ceramide synthesis.
Academic Article
The hyperglycemia-induced inflammatory response in adipocytes: the role of reactive oxygen species.
Academic Article
Alternative splicing generates two different mRNA species for rat link protein.
Academic Article
Persistence of Pancreatic Insulin mRNA Expression and Proinsulin Protein in Type 1 Diabetes Pancreata.
Grant
Mitogenic Signal Transduction in Pancreatic Beta-Cells
Grant
Metabolic Control of Proinsulin Biosynthesis Translation
Grant
Metabolic Control of Proinsulin Biosynthesis Translation
Search Criteria
RNA Messenger